As you know from the introduction to this book, PRP (or platelet rich plasma) comes from a person’s own blood (autologous) and can be used to stimulate multipotent stem cells to rejuvenate new tissue.

But, why would a woman decide she wants a shot in the vagina using her own blood!?

For the past year, Laura had watched me inject people and rejuvenate the face and the breasts. She actually had the procedure done more than once and saw her face improve in color, texture, and shape with a procedure I invented, the Vampire Facelift ®.  

Also, she had regained sensation in her breasts (which she had lost due to breast implants and breastfeeding 3 children) with aprocedure I designed called the  Vampire Breast Lift ®. So, she knew the rejuvenating effects of PRP (from both face and breast) and wanted to see if an injection of PRP into her vagina would help. 

She had delivered 3 children and wanted to see if PRP would make her vagina feel tighter. Also, she was able to have an orgasm but still had some difficulty with multiple orgasms and wanted also to see if the PRP would help tighten things up and improve her orgasms. 

 Laura Ezekiel (the woman who helped me think of the O-Shot® procedure)

I thought since there are no know serious side effects from the use of PRP anywhere in the body (and there are thousands of research papers), “We’ll try it and see what happens.”

I took her to the office.

To isolate platelet rich plasma (PRP), I drew blood from her arm (just like if she were giving blood at the laboratory for a test).

As part of the strategy of where to put the injection, I used ideas that I explain in a book I wrote about how to teach women to understand her body better and become able to ejaculate.  I had already taught Laura to ejaculate, but placed part of the PRP in the areas most responsible for this response (more about that in the next chapter).

I drew Laura’s blood and centrifuged it.  Then, I added the calcium chloride, which is like salt water (sodium chloride), only calcium instead of sodium.  The calcium chloride signals the platelets that there’s been a tissue injury.

Usually, calcium concentrations in tissue exceed those in the blood.  When tissue sustains an injury, then calcium’s released from the injured tissue.  When calcium, which is normally in the lower concentration in the blood stream, becomes higher in concentration in the blood, then the platelets “think,”  “Oh, there’s been an injury!  Let’s signal for repair to start.”

Then the thrombin cascade activates causing a clot that stops the bleeding.  The platelets also release at least 7 powerful growth factors that we know about so far (there could be more). These growth factors stimulate multipotent stem cells to rejuvenate the tissue.

If you want to know what works, look at what the NFL does to keep their athletes going. If someone’s making 10 million dollars a year and they miss a day of work that’s sort of expensive. One of the things they do is use platelet rich plasma to rejuvenate the tissue of the joints. Why shouldn’t a woman enjoy the same rejuvenating benefits that help an elite athlete run down the football field to help her develop a healthier body—including improvement of the vaginal tissue needed for sex and urination?

Also, since physicians have been searching for over 15 years for something that can be injected around the urethra to cure urinary incontinence, I knew from that research that putting a needle in the vaginal area is safe (previous attempts to discover a method gave side effects not from the needle but from the material injected).  A much larger needle than I intended to use in that area can be used to drain the bladder with no ill effects from the needle.

Knowing that PRP also causes no side effects and that needles in that area cause no serious injury, I thought, “Okay, it could work! I’ll possibly give her the same rejuvenation benefits enjoyed by the NFL and racehorses (new healthier tissue) if I give her PRP in the vagina.”

I gave her the shot and in the process of doing that, I went ahead and injected some of that plasma where I knew Laura collected fluid when she ejaculated.

I did not even need a speculum; all the important structures I wanted to rejuvenate can be easily seen near the opening of the vagina with nothing more than a strong lamp.

I also thought,  “While I’m at it (knowing the anatomy of the vagina and knowing that most of the clitoris is within the body and knowing how plasma behaves like water) I’ll inject the part of the clitoris that’s visible and hopefully rejuvenate the whole structure.”

When I injected her clitoris, rather than the clitoris swelling out, as expected, the fluid disappeared within Laura’s body, travelling into each side of the inner clitoris. I couldn’t see it but I could see that a much greater volume than what was exposed of the clitoris was actually injected into it—yet the clitoris did not expand, it just absorbed. The PRP had to go somewhere and observation was that it was going into the depths of her clitoris to rejuvenate that tissue.

After the procedure, Laura put her dress back on and we went to dinner. I expected maybe 2-3 weeks later she might see some benefit.

Her body would give me a huge surprise.

Although her reaction interested me, I grew puzzled over the fact that her response happened before the stem cells could actually grow new tissue.

Why?

Before I tell you my hypothesis about what happened, think back to Dr. Gräfenberg. He thought that every part of a woman’s body is potentially erotic and I agree with that. But, he thought of the whole female body, the most erotic part is the urethra.

Having worked in the emergency room in the past, I remember seeing x-ray photographs where women lost little things up in the urethra because they put them in the urethra for sexual stimulation

Dr. Gräfenberg thought encouraged stimulating the urethra through the roof of the vagina by manual pressure and particularly in the part where the urethra joins the bladder.  From that idea came the “The G-spot” (named after Dr. Gräfenberg).

Where I gave the shot was more proximal than the area usually considered the G-Spot:  between the vaginal wall and the urethra at the spot where the Skenes glands collect fluid.

When a woman ejaculates, the fluid from the Skene’s glands is what accounts for the fluid that comes from her body.  We now know from ultrasound studies and from biochemical analyses that the “female prostate,” the Skene’s glands (just like the prostate gland of men) contributes to the fluid of the ejaculate by excreting fluid into the urethra. The fluid from the Skene’s glands even tests positive for prostate specific antigen (PSA), normally considered to be associated only with men!

Just as different men might have different sized prostate glands, so might a woman have more or less Skene’s glands. I postulated that when I injected the vagina, it might help this tissue become healthier and enhance pleasure and perhaps even enhance ejaculation.  So, I placed the injection where I knew to be the location of Laura’s Skene’s glands.

Consider riding a roller coaster:  you’re going to experience more of a thrill if there’s a longer fall from a taller hill. In the same way, arousal and orgasm will be heightened if the fluid that’s released is increased in volume. Relief of sexual tension (orgasm) feels enhanced if the sexual tension is enhanced with more fluid.

It turns out that Laura’s hyper-sexuality (which was almost a nuisance to her because of the extreme intensity) went away by the end of the first week. Even though Laura was very sexual before the shot, it became extremely urgent for her to have sex and orgasms grew more intense and more powerful right from the start. Then it faded some just like we’ve seen when we inject platelet rich plasma into other tissue.

The more long lasting effects started to appear around the third week as those multipotent stem cells grew new tissue.  We know from biopsy studies of other parts of the body that new tissue includes fibroblast and glandular tissue and bone and whatever happens to be there.

In the skin, where there are fat cells, the fat cells enlarge and multiply. The best way to think about PRP:  it’s like that yellow goo that was around the scab when you scraped your knee when you fell as a child. You had to grow new skin to replace what had been peeled away when you fell. And it’s that yellow goo around the scab where the growth factors are embedded; that’s what I was making when I injected the plasma into Laura’s vagina.

Three weeks later, she indeed became even more easily aroused and although the hyper-sexuality of needing sex continuously was relieved, when we did have sex, it felt tighter us both and her ejaculations became much more intense, her orgasms became more easily achieved, and vaginally-produced orgasms (with penis-in-vagina) became more easily found.

You might think, “Well, this is sort of like trick circus sex, where a shot somehow makes a woman able to do something that she wasn’t able to do.”

Some people think of female ejaculation as just a little extra trick. It’s much more than that. It’s about having a healthy body, every part of the body, including the genitals at full function.

A mountain of research supports the idea that there’s a different type of connection with different types of orgasm.  If sex makes a connection between people that establishes relationships like families and marriage and love, then that supports people. If you believe that love and relationships and connections are important and that sex somehow contributes to those connections, then I think it might make sense that it’s worth while to do something with a woman’s own natural growth factors to encourage healing and enhancement of that natural health and that way of connecting—through sexuality.

When I began offering this procedure to my patients, I called it the “O-Shot®” or “Orgasm Shot®” and trademarked the name to keep the rare quack from misleading people with the name. A few months later, I started teaching the procedure to other physicians. Only certified physicians can legally use the name.  Others may make PRP and inject it, but there’s a wide variation in how the PRP can be made; at last count, there’s 19 lab kits approved by the FDA for prepartion of PRP for injection back into the body–all of them working a little differently.  Also, there could be a very wide variation in how the injection can be done!To complicate things, though the FDA controls the kits that are offered to physicians for prepeartion of PRP,  the FDA does not control how blood products are used.  Only the woman’s blood (no drug) is used in the procedure.

So, I thought it important to make sure that women know what they’re getting with a procedure that involves such an important part of their life.  The trademarked name gives a way to be reassure a woman that she’s seeing someone properly trained.

So, Laura was the first to receive the O-Shot ® procedure ever in the world and I’m forever grateful (and many women will be grateful) to Laura for her courage to want to be the first.

Remember, only 14% of women in their entire life, by a recent study published in obstetrics and gynecology ever have a conversation with their physician about sex even though 40-60% of them have problems that seriously bother them. Research shows that physicians try to avoid the subject because they don’t, at the present time, have general knowledge of the O-Shot ® and the ways to help with sexual problems.

Everyone seems to avoid the problem or discussing the problem.  Surprisingly even some of the sex therapists and surprisingly even women seem to violently, almost in an evil sort of way, attack other women who want to have better sexual health.

So, it took a combination of Laura’s courage and trust in me as well as my understanding of female sexual function and anatomy to conceive of the procedure.  I could not have done it without her.

I treated around 20 other women over the next 2 months before finally offering to teach the procedure to other physicians.

Some have tried to claim helping think of the O-Shot ® procedure (and steal Laura’s credit), but I want to make sure everyone knows—no other physician helped me think of this idea though many will research it in the future. The only other person who helped me think of this procedure was a very courageous woman, Laura Ezekiel.

I hope that you will open the idea that whatever is available to help an NFL athlete run faster to carry a football (PRP) should be considered at least (and offered when appropriate) to women who might want to have more sexual pleasure and better vaginal health. This is not mutilation, this is not even surgery, there is no scalpel, there is no foreign body; this is a woman’s own natural healing factors, from her own body.  With the O-Shot® procedure, the physician uses the same factors that woman’s body used to heal a scraped knee when she was young girl.

Why shouldn’t a 50-year old woman who’s trying to maintain the relationship with her husband and avoid peeing on her leg when she goes for a walk or when she coughs at work—why shouldn’t she have that same technology available to her that’s available to an Olympic athlete or a thoroughbred horse?

I’m begging you to not attack the women who display the courage to try this new therapy and I’m begging you to ask your gynecologists to look carefully at the science behind the procedure.

This is not a drug, this is not something where there’s millions of dollars available for research because there’s no drug. There’s no attractive woman sales person that’s going to walk into gynecologist’s office and say, “Dr., you should prescribe this.”  Because this involves only the woman’s own blood, the entire research project (thus far) was financed by the physicians participating in the research.

I promise you that if a drug that could do what the O-Shot ® procedure does, this would be all over your TV and you’d be seeing commercials about it—but because there’s no drug company with millions of dollars to be made, and because insurance doesn’t yet pay for it, most doctors don’t know about it.

This is important and I hope that you’ll help us by forwarding this information to your friends and to your doctor.

This O-Shot ® procedure is a real adventure in medicine.

The first heart catheterization was done in the 1940’s and the doctor was kicked out of the hospital and got so depressed, he wound up in an insane asylum even though he had the courage to do the first heart cath on himself.  But, the heart catheterization wasn’t commonly done until the 1970’s, 30 years later.

Do not let that happen with the O-Shot ® procedure.

On average, it takes 10 years to prove a new therapy in medicine.  Then, once it’s proven, once you have one research study, and people attack it then there’s more research.  New things in medicine evolve with a very gradual acceptance as more research is done.

Then surprisingly, many physicians still won’t offer a new therapy unless insurance pays for it because they don’t have enough time (they’re working so hard already) to do things for free.

So, usually 10 years passes before the herd of sheep-physicians finally say, “Okay, we can start now, since this is proven.”

Then another 10 years passes before the whole herd starts doing the new procedure.  So usually it takes10 years to prove a new therapy and another 10 years before it’s commonly done – 20 years total from conception to common use. Please help shorten this time frame with the O-Shot ® procedure.  Please consider the 50 million women in the US alone who need this for sexual function and 20 million women in the US who need it for urinary incontinence.

Question:  Do you know the number one reason for a women going to a nursing home?

Answer:  It’s urinating on the floor because…the family will keep grandmother at home even with dementia, even with frailty; but when grandmother can’t hold her urine, then she becomes a hygiene problem and too much work.

So, when grandmother can’t get to the bathroom without urinating on the floor, that is the most common reason for finally giving up and putting her in the nursing home. Because the O-Shot ® will usually stop urinary incontinence without the side effects of anti-cholinergic medicines and the risks of surgery, this represents a breakthrough in women’s health. For the sake of all the grandmothers, I’m pleading: think about it, look at it, convince yourself; then, show your friends and your doctor.

You’ll find more details and all the certified providers listed at www.OShot.info.